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KMID : 0352519850220010325
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Korea Univercity Medical Journal
1985 Volume.22 No. 1 p.325 ~ p.333
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A Study of Serum Immunoglobulins in the Term Pregnant Women and Their Neonates
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申載昇/Shin, Jae Seung
金善行/洪性鳳/Kim, Sun Haeng/Hong, Sung Bong
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Abstract
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Levels of the three major classic immunoglobulins(IgG, IgA, IgM) were measured by radial immunodiffusion plate method in paired maternal and cord sera at the time of delivery.
Primarily, the purpose of this study is to establish the baseline of serum immunoglobulin levels in the normal term pregnant women and their fetuses in Korea, and to evaluate the correlations between serum immunoglobulin levels and various factors which were proposed that can influence the serum concentrations of immunoglobulins.
The values obtained in maternal and fetal sera were submitted to statistical analysis to know the correlations with delivery method, parity, fetal body weight and monthly expenditure.
1. The levels of IgG in maternal and cord sera were 1129±19.9mg per 100ml and 1245±26.2mg per 100ml.
2. The levels of IgA in maternal and cord sera were 225±7.1mg per 100m1 and 27±4.2 mg per 100ml.
3. The levels of IgM in maternal and cord sera were 155±3.5mg per 100ml and 40±2.1 mg per 100m1.
4. There was no close correlation between the immunoglobulin levels in the maternal sera and the fetal body weight.
5. There was no close correlation between the immunoglobulin levels in the maternal sera and the monthly expenditure.
6. There was no significant difference in maternal and fetal cord sera immunoglobulins levels between normal vaginal delivery group and elective cesarean section group.
7. There was no significant difference in maternal and fetal cord sera immunoglobulins levels between primiparous group and multiparous group.
8. There was siginificant correlation between the IgM levels of mother and the fetus, but not in IgG and IgA.
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KEYWORD
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